So, if you are eating, drinking, or otherwise consuming more than
one substance, they may impact each others bioavailabilities. And
you're correct that grapefruit juice might interact with other
food and drugs a person consumes, which is why the consumption of
grapefruit products are discouraged when using certain
medications. Intrigued? Read on for more info on how it happens.
The small intestine has an enzyme called CYP3A4, which often
helps with drug metabolism. However, grapefruit juice (and
grapefruits themselves) may stop CYP3A4 from working properly,
leading to more of a drug entering the bloodstream instead of
being broken down in the small intestine.
------------------------------------------quoted from Go Ask
Alice!---
to be continued;
・substance (音)sΛ'bstэns (名)物質、実体、実質、内容
The substance is far more essential than the form.
内容は形式よりもはるかに重要である。
・bioavailability (音)ba`iouΛ`veilэbi'liti (名)バイオアベイラビリティ、生物学的利用能、生体利用効率、生体利用性
Bioavailability ranges from 75 to 85%.
バイオアベイラビリティーは75?85％の範囲です。
・interact (音)i`ntэrae'kt (自動)交流する、ふれあう、作用する、影響する
I studied Chinese and did my best to interact with Chinese
people.
私は中国語を勉強しできるだけ中国の方々と交流するように心掛けました。
・consumption (音)kэnsΛ'mp∫эn (名)飲食、食物摂取、消費、消費量
That car has good fuel consumption.
その車は燃費が良い。
・discourage (音)diskэ':ridз (他動)やる気をそぐ、がっかりさせる、やめさせる、思いとどまらせる
I highly discourage you against quitting your job.
仕事を辞めるなんてぜひとも思いとどまるよう勧めるよ。
・medication (音)me'dike`i∫n (名)薬剤、医薬、投薬
It's time for your medication. 薬の時間です。
・intrigue (音)intri':g (他動)興味を引き付ける、好奇心をそそる
Facts intrigue me. 私は事実に興味がある。
・read on 読み続ける、読める
I read on my commute.
私は通勤時間に本を読みます。
・intestine (音)intes'tin (名)腸
Lactase is produced in the small intestine.
乳糖分解酵素は小腸で作られる。・enzyme (音)e'nzaim (名)酵素
It blocks enzymes that repair damage to DNA. それはDNAの損傷を修復する酵素を阻害する働きがある。
・metabolism (音)mэtae'bэli`zm (名)新陳代謝、代謝作用、同化作用
Our bodies are subject to constant metabolism.
体は常に新陳代謝する。
・bloodstream (音)blΛ'dstri:m (名)血流
The endocrine is any of the glands of the endocrine system
that secrete hormones directly into the bloodstream.
内分泌腺は血流にホルモンを直接分泌する内分泌系の腺の総称です。
■構文チェック! 覚えておくと、会話力がつきまます。
・そのため、もしあなたが複数の物質を食べたり飲んだりしたなら、
So, if you are eating, drinking, or otherwise consuming more
than one substance,
・それぞれの物質の生物学的利用能に影響を与える可能性があります。
they may impact each others bioavailabilities.
・そして〜というのはその通りです。
And you're correct that 〜.
・グレープフルーツジュースは他の食物や薬物と相互に作用する可能性があるため、 grapefruit
juice might interact with other food and drugs a person consumes,
・特定の薬を使用している場合はグレープフルーツ製品の摂取を控える必要がある
which is why the consumption of grapefruit products are
discouraged when using certain medications.
・興味がおありですか？
Intrigued?
・どうなっているかをもっと知りたいときはこちらを読みなさい。
Read on for more info on how it happens.
・小腸にはCYP3A4と呼ばれる酵素があり、しばしば薬物の代謝を助ける。
The small intestine has an enzyme called CYP3A4, which often
helps with drug metabolism.
・しかし、グレープフルーツジュース（およびグレープフルーツ自体）は、CYP3A4が正しく働くのを阻害し、小腸で分解される代わりに血液中にもっと入ってしまう可能性があります。
However, grapefruit juice (and grapefruits themselves) may
stop CYP3A4 from working properly, leading to more of a drug
entering the bloodstream instead of being broken down in the
small intestine.
そのため、もしあなたが複数の物質を食べたり飲んだりしたなら、それぞれの物質の生物学的利用能に影響を与える可能性があるわ。
→So, if you are eating, drinking, or otherwise consuming more
than one substance, they may impact each others
bioavailabilities.
そして、グレープフルーツジュースは他の食物や薬物と相互に作用する可能性があるため、特定の薬を使用している場合はグレープフルーツ製品の摂取を控える必要があるというのはその通りだわ。
→And you're correct that grapefruit juice might interact with
other food and drugs a person consumes, which is why the
consumption of grapefruit products are discouraged when using
certain medications.
興味がおあり？
→Intrigued?
どうなっているかをもっと知りたいときはこちらを読みなさい。
→Read on for more info on how it happens.
小腸にはCYP3A4と呼ばれる酵素があり、しばしば薬物の代謝を助けるわ。
→The small intestine has an enzyme called CYP3A4, which often
helps with drug metabolism.
でも、グレープフルーツジュース（グレープフルーツ自体も）は、CYP3A4が正しく働くのを阻害し、小腸で分解される代わりに血液中にもっと入ってしまう可能性があるわ。
→However, grapefruit juice (and grapefruits themselves) may
stop CYP3A4 from working properly, leading to more of a drug
entering the bloodstream instead of being broken down in the
small intestine.
■暗唱練習
So, if you are eating, drinking, or otherwise consuming more than
one substance, they may impact each others bioavailabilities. And
you're correct that grapefruit juice might interact with other
food and drugs a person consumes, which is why the consumption of
grapefruit products are discouraged when using certain
medications. Intrigued? Read on for more info on how it happens.
The small intestine has an enzyme called CYP3A4, which often
helps with drug metabolism. However, grapefruit juice (and
grapefruits themselves) may stop CYP3A4 from working properly,
leading to more of a drug entering the bloodstream instead of
being broken down in the small intestine.
ピーコックの初期の対話風刺小説であるHeadlong
Hall (1816)は、存命中最も人気があり代表作とされています。
音楽、美食、哲学、政治、クラニオロギー、絵画、造園など、さまざまな要素が盛り込まれた知的喜劇です。
・・・・・・
Thomas Love Peacock (1785-1866) is one of the most distinctive
prose satirists of the Romantic period. The Cambridge Edition of
the Novels of Thomas Love Peacock offers the first complete text
of these works to appear for more than half a century. Headlong
Hall (1816), Peacock's earliest work of dialogic and satirical
fiction, was the most popular of his tales during his lifetime
and considered his signature novel. An episodic plot and a
country house setting provide the framework for a sparkling
intellectual comedy that embraces music, gastronomy, philosophy,
politics, craniology, painting, and landscape gardening.
(amazon.com)
THE HUNGER GAMES: THE BALLAD OF SONGBIRDS & SNAKES follows a
young Coriolanus (Tom Blyth) who is the last hope for his failing
lineage, the once-proud Snow family that has fallen from grace in
a post-war Capitol. With his livelihood threatened, Snow is
reluctantly assigned to mentor Lucy Gray Baird (Rachel Zegler), a
tribute from the impoverished District 12. But after Lucy Gray's
charm captivates the audience of Panem, Snow sees an opportunity
to shift their fates. With everything he has worked for hanging
in the balance, Snow unites with Lucy Gray to turn the odds in
their favor. Battling his instincts for both good and evil, Snow
sets out on a race against time to survive and reveal if he will
ultimately become a songbird or a snake.
(rottentomatoes.com)